ILD (Interstitial lung disease)

lung cancer

What Is ILD (Interstitial lung disease)?

Interstitial (in-tur-STISH-ul) lung disease describes a large group of disorders, most of which cause progressive scarring of lung tissue. The scarring associated with interstitial lung disease eventually affects your ability to breathe and get enough oxygen into your bloodstream.

Interstitial lung disease can be caused by long-term exposure to hazardous materials, such as asbestos. Some types of autoimmune diseases, such as rheumatoid arthritis, also can cause interstitial lung disease. In some cases, however, the causes remain unknown.

Once lung scarring occurs, it’s generally irreversible. Medications may slow the damage of interstitial lung disease, but many people never regain full use of their lungs. A lung transplant is an option for some people who have interstitial lung disease.

Causes of interstitial lung disease (ILD)

  • LD related to another health disorder: Some people develop ILD as a result of having an autoimmune disease (the immune system harms the body). Examples of autoimmune diseases include rheumatoid arthritis, scleroderma, polymyositis/dermatomyositis, lupus and sarcoidosis.
  • ILD caused by breathing in harmful substances: People who breathe harmful particles such as coal dust, asbestos, tobacco smoke or hairdressing chemicals may develop ILD.
  • Genetic ILD: A genetic ILD occurs when the disease is passed down among family members. These conditions include neurofibromatosis (a disease in which tumors grow on nerves) and Gaucher disease (marked by enlargement of internal organs, including the spleen and liver, and lesions on the bones).
  • Idiopathic ILD: Idiopathic means the cause is not known. Idiopathic ILD usually affects people over 60 years old.

Symptoms of interstitial lung disease

  • Shortness of breath
  • Coughing, typically nonproductive
  • Decreased exercise tolerance
  • Fatigue
  • Weight loss